STAT5 and CD4 (+) T Cell Immunity

STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4 (+) helper and regulatory T-cell subsets.

Detalles Bibliográficos
Autores principales: Owen, David L., Farrar, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247784/
https://www.ncbi.nlm.nih.gov/pubmed/28163905
http://dx.doi.org/10.12688/f1000research.9838.1
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author Owen, David L.
Farrar, Michael A.
author_facet Owen, David L.
Farrar, Michael A.
author_sort Owen, David L.
collection PubMed
description STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4 (+) helper and regulatory T-cell subsets.
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spelling pubmed-52477842017-02-02 STAT5 and CD4 (+) T Cell Immunity Owen, David L. Farrar, Michael A. F1000Res Review STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4 (+) helper and regulatory T-cell subsets. F1000Research 2017-01-11 /pmc/articles/PMC5247784/ /pubmed/28163905 http://dx.doi.org/10.12688/f1000research.9838.1 Text en Copyright: © 2017 Owen DL and Farrar MA http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Owen, David L.
Farrar, Michael A.
STAT5 and CD4 (+) T Cell Immunity
title STAT5 and CD4 (+) T Cell Immunity
title_full STAT5 and CD4 (+) T Cell Immunity
title_fullStr STAT5 and CD4 (+) T Cell Immunity
title_full_unstemmed STAT5 and CD4 (+) T Cell Immunity
title_short STAT5 and CD4 (+) T Cell Immunity
title_sort stat5 and cd4 (+) t cell immunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247784/
https://www.ncbi.nlm.nih.gov/pubmed/28163905
http://dx.doi.org/10.12688/f1000research.9838.1
work_keys_str_mv AT owendavidl stat5andcd4tcellimmunity
AT farrarmichaela stat5andcd4tcellimmunity

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