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Effects of LRRK2 Inhibitors on Nigrostriatal Dopaminergic Neurotransmission
INTRODUCTION: Mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment for PD...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248597/ https://www.ncbi.nlm.nih.gov/pubmed/27943591 http://dx.doi.org/10.1111/cns.12660 |