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Proteomic and genomic characterization of a yeast model for Ogden syndrome

Naa10 is an N(α)‐terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co‐translationally acetylates the α‐amino group of newly synthetized proteins as they emerge from the ribosome. Roughly 40–50% of the human proteome is acetylated by Naa10, rendering this an enzyme one o...

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Detalles Bibliográficos
Autores principales: Dörfel, Max J., Fang, Han, Crain, Jonathan, Klingener, Michael, Weiser, Jake, Lyon, Gholson J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248646/
https://www.ncbi.nlm.nih.gov/pubmed/27668839
http://dx.doi.org/10.1002/yea.3211