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Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo

The roles of ginsenoside compound K (CK) in inhibiting tumor have been widely recognized in recent years. However, low water solubility and significant P-gp efflux have restricted its application. In this study, CK ascorbyl palmitate (AP)/d-α-tocopheryl polyethylene glycol 1000 succinate monoester (...

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Detalles Bibliográficos
Autores principales:	Zhang, Youwen, Tong, Deyin, Che, Daobiao, Pei, Bing, Xia, Xiaodong, Yuan, Gaofeng, Jin, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248941/ https://www.ncbi.nlm.nih.gov/pubmed/28144142 http://dx.doi.org/10.2147/IJN.S119226

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