The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Pharmacological activation of the hypothalamic glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) promotes weight loss and improves glucose tolerance. This demonstrates that the hypothalamic GLP-1R is sufficient but does not show whether it is necessary for the effects of exogenous GLP-1R agonists (G...

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Autores principales: Burmeister, Melissa A., Ayala, Jennifer E., Smouse, Hannah, Landivar-Rocha, Adriana, Brown, Jacob D., Drucker, Daniel J., Stoffers, Doris A., Sandoval, Darleen A., Seeley, Randy J., Ayala, Julio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248999/
https://www.ncbi.nlm.nih.gov/pubmed/27908915
http://dx.doi.org/10.2337/db16-1102

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