Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC gene

BACKGROUND: Germline mutations in the coding sequence of the tumour suppressor APC gene give rise to familial adenomatous polyposis (which leads to colorectal cancer) and are associated with many other oncopathologies. The loss of APC function because of deletion of putative promoter 1A or 1B also r...

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Detalles Bibliográficos
Autores principales: Matveeva, Marina Yu, Kashina, Elena V., Reshetnikov, Vasily V., Bryzgalov, Leonid O., Antontseva, Elena V., Bondar, Natalia P., Merkulova, Tatiana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249005/
https://www.ncbi.nlm.nih.gov/pubmed/28105931
http://dx.doi.org/10.1186/s12863-016-0460-8

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