A physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioning

BACKGROUND: Drug repositioning can reduce the time, costs and risks of drug development by identifying new therapeutic effects for known drugs. It is challenging to reposition drugs as pharmacological data is large and complex. Subnetwork identification has already been used to simplify the visualiz...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yahui, Hameed, Pathima Nusrath, Verspoor, Karin, Halgamuge, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249043/
https://www.ncbi.nlm.nih.gov/pubmed/28105946
http://dx.doi.org/10.1186/s12918-016-0371-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249043/
https://www.ncbi.nlm.nih.gov/pubmed/28105946
http://dx.doi.org/10.1186/s12918-016-0371-3

Ejemplares similares