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A physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioning
BACKGROUND: Drug repositioning can reduce the time, costs and risks of drug development by identifying new therapeutic effects for known drugs. It is challenging to reposition drugs as pharmacological data is large and complex. Subnetwork identification has already been used to simplify the visualiz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249043/ https://www.ncbi.nlm.nih.gov/pubmed/28105946 http://dx.doi.org/10.1186/s12918-016-0371-3 |