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Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

Site-2 proteases (S2P) belong to the M50 family of metalloproteases, which typically perform essential roles by mediating activation of membrane–bound transcription factors through regulated intramembrane proteolysis (RIP). Protease-dependent liberation of dormant transcription factors triggers dive...

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Detalles Bibliográficos
Autores principales:	Koussis, Konstantinos, Goulielmaki, Evi, Chalari, Anna, Withers-Martinez, Chrislaine, Siden-Kiamos, Inga, Matuschewski, Kai, Loukeris, Thanasis G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249076/ https://www.ncbi.nlm.nih.gov/pubmed/28107409 http://dx.doi.org/10.1371/journal.pone.0170260

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