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Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure
The only evidence of vaccine-induced protection from HIV acquisition in humans was obtained in the RV144 HIV vaccine clinical trial. One immune correlate of risk in RV144 was observed to be higher titers of vaccine-induced antibodies (Abs) reacting with a 23-mer non-glycosylated peptide with the sam...
Autores principales: | Aiyegbo, Mohammed S., Shmelkov, Evgeny, Dominguez, Lorenzo, Goger, Michael, Battacharya, Shibani, deCamp, Allan C., Gilbert, Peter B., Berman, Phillip W., Cardozo, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249078/ https://www.ncbi.nlm.nih.gov/pubmed/28107435 http://dx.doi.org/10.1371/journal.pone.0170530 |
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