Cargando…

Parenclitic Network Analysis of Methylation Data for Cancer Identification

We make use of ideas from the theory of complex networks to implement a machine learning classification of human DNA methylation data, that carry signatures of cancer development. The data were obtained from patients with various kinds of cancers and represented as parenclictic networks, wherein nod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karsakov, Alexander, Bartlett, Thomas, Ryblov, Artem, Meyerov, Iosif, Ivanchenko, Mikhail, Zaikin, Alexey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249089/ https://www.ncbi.nlm.nih.gov/pubmed/28107365 http://dx.doi.org/10.1371/journal.pone.0169661

Ejemplares similares

Parenclitic and Synolytic Networks Revisited
por: Nazarenko, Tatiana, et al.
Publicado: (2021)

Parenclitic networks for predicting ovarian cancer
por: Whitwell, Harry J., et al.
Publicado: (2018)

Variations in the Intragene Methylation Profiles Hallmark Induced Pluripotency
por: Druzhkov, Pavel, et al.
Publicado: (2015)

Parenclitic networks: uncovering new functions in biological data
por: Zanin, Massimiliano, et al.
Publicado: (2014)

Prognosis and Survival Modelling in Cirrhosis Using Parenclitic Networks
por: Zhang, Han, et al.
Publicado: (2022)

A DNA Methylation Network Interaction Measure, and Detection of Network Oncomarkers
por: Bartlett, Thomas E., et al.
Publicado: (2014)

Parenclitic Network Mapping Identifies Response to Targeted Albumin Therapy in Patients Hospitalized With Decompensated Cirrhosis
por: Oyelade, Tope, et al.
Publicado: (2023)

Transforming Lindblad Equations into Systems of Real-Valued Linear Equations: Performance Optimization and Parallelization of an Algorithm
por: Meyerov, Iosif, et al.
Publicado: (2020)

The Human Body as a Super Network: Digital Methods to Analyze the Propagation of Aging
por: Whitwell, Harry J., et al.
Publicado: (2020)

Performance and Scalability Analysis of CNN-based Deep Learning Inference in the Intel Distribution of OpenVINO Toolkit
por: Meyerov, Iosif
Publicado: (2019)

Modeling Working Memory in a Spiking Neuron Network Accompanied by Astrocytes
por: Gordleeva, Susanna Yu., et al.
Publicado: (2021)

Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer
por: Bartlett, Thomas E., et al.
Publicado: (2013)

Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear
por: Vershinina, O., et al.
Publicado: (2021)

Multi-Input Distributed Classifiers for Synthetic Genetic Circuits
por: Kanakov, Oleg, et al.
Publicado: (2015)

ML-Based Analysis of Particle Distributions in High-Intensity Laser Experiments: Role of Binning Strategy
por: Rodimkov, Yury, et al.
Publicado: (2020)

Systems Medicine of Cancer: Bringing Together Clinical Data and Nonlinear Dynamics of Genetic Networks
por: Blyuss, Konstantin B., et al.
Publicado: (2016)

Towards ML-Based Diagnostics of Laser–Plasma Interactions
por: Rodimkov, Yury, et al.
Publicado: (2021)

Interplay between Path and Speed in Decision Making by High-Dimensional Stochastic Gene Regulatory Networks
por: Nené, Nuno R., et al.
Publicado: (2012)

Parameter Estimation Methods for Chaotic Intercellular Networks
por: Mariño, Inés P., et al.
Publicado: (2013)

A comparison of Monte Carlo-based Bayesian parameter estimation methods for stochastic models of genetic networks
por: Mariño, Inés P., et al.
Publicado: (2017)

Novel Algorithm of Network Calcium Dynamics Analysis for Studying the Role of Astrocytes in Neuronal Activity in Alzheimer’s Disease Models
por: Mitroshina, Elena V., et al.
Publicado: (2022)

Disease classification for whole-blood DNA methylation: Meta-analysis, missing values imputation, and XAI
por: Kalyakulina, Alena, et al.
Publicado: (2022)

Integrative survival analysis of breast cancer with gene expression and DNA methylation data
por: Bichindaritz, Isabelle, et al.
Publicado: (2021)

Employing machine learning for theory validation and identification of experimental conditions in laser-plasma physics
por: Gonoskov, A., et al.
Publicado: (2019)

Asymmetry in Erythroid-Myeloid Differentiation Switch and the Role of Timing in a Binary Cell-Fate Decision
por: Alagha, Afnan, et al.
Publicado: (2013)

Integrated Information as a Measure of Cognitive Processes in Coupled Genetic Repressilators
por: Abrego, Luis, et al.
Publicado: (2019)

Editorial: Multiscale Modeling of Rhythm, Pattern and Information Generation: from Genome to Physiome
por: Chen, Shangbin, et al.
Publicado: (2020)

Computing and networking at JINR
por: Zaikin, N S, et al.
Publicado: (2001)

Extreme plasma states in laser-governed vacuum breakdown
por: Efimenko, Evgeny S., et al.
Publicado: (2018)

Controlling synchronization of gamma oscillations by astrocytic modulation in a model hippocampal neural network
por: Makovkin, Sergey, et al.
Publicado: (2022)

Integrated Information in the Spiking–Bursting Stochastic Model
por: Kanakov, Oleg, et al.
Publicado: (2020)

Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system
por: Tieri, Paolo, et al.
Publicado: (2010)

Algorithms and architectures for parallel processing: ICA3PP 2016 collocated workshops SCDT, TAPEMS, BigTrust, UCER, DLMCS, Granada, Spain, December 14-16, 2016, proceedings
por: Garcia-Blas, Javier, et al.
Publicado: (2016)

Analysis of human mitochondrial genome co-occurrence networks of Asian population at varying altitudes
por: Verma, Rahul K., et al.
Publicado: (2021)

Identification of key genes in glioma CpG island methylator phenotype via network analysis of gene expression data
por: Bo, Lijuan, et al.
Publicado: (2017)

Fusion of single-cell transcriptome and DNA-binding data, for genomic network inference in cortical development
por: Bartlett, Thomas
Publicado: (2021)

Speed-Dependent Cellular Decision Making in Nonequilibrium Genetic Circuits
por: Nené, Nuno R., et al.
Publicado: (2012)

Effect of Noise in Intelligent Cellular Decision Making
por: Bates, Russell, et al.
Publicado: (2015)

Unraveling Aβ-Mediated Multi-Pathway Calcium Dynamics in Astrocytes: Implications for Alzheimer’s Disease Treatment From Simulations
por: Liu, Langzhou, et al.
Publicado: (2021)

An Account of Models of Molecular Circuits for Associative Learning with Reinforcement Effect and Forced Dissociation
por: Li, Zonglun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ie0mvit23qm7s63bcns12ern6i