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Systemic T Cells Immunosuppression of Glioma Stem Cell-Derived Exosomes Is Mediated by Monocytic Myeloid-Derived Suppressor Cells
A major contributing factor to glioma development and progression is its ability to evade the immune system. Nano-meter sized vesicles, exosomes, secreted by glioma-stem cells (GSC) can act as mediators of intercellular communication to promote tumor immune escape. Here, we investigated the immunomo...
Autores principales: | Domenis, Rossana, Cesselli, Daniela, Toffoletto, Barbara, Bourkoula, Evgenia, Caponnetto, Federica, Manini, Ivana, Beltrami, Antonio Paolo, Ius, Tamara, Skrap, Miran, Di Loreto, Carla, Gri, Giorgia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249124/ https://www.ncbi.nlm.nih.gov/pubmed/28107450 http://dx.doi.org/10.1371/journal.pone.0169932 |
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