Cargando…

Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System

OBJECTIVE: In this work we set to develop and to validate a new in vivo frameless orthotopic Diffuse Intrinsic Pontine Glioma (DIPG) model based in the implantation of a guide-screw system. METHODS: It consisted of a guide-screw also called bolt, a Hamilton syringe with a 26-gauge needle and an insu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marigil, Miguel, Martinez-Velez, Naiara, Domínguez, Pablo D., Idoate, Miguel Angel, Xipell, Enric, Patiño-García, Ana, Gonzalez-Huarriz, Marisol, García-Moure, Marc, Junier, Marie-Pierre, Chneiweiss, Hervé, El-Habr, Elías, Diez-Valle, Ricardo, Tejada-Solís, Sonia, Alonso, Marta M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249159/ https://www.ncbi.nlm.nih.gov/pubmed/28107439 http://dx.doi.org/10.1371/journal.pone.0170501

Ejemplares similares

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models
por: Martínez-Vélez, Naiara, et al.
Publicado: (2019)

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models
por: Martinez-Velez, Naiara, et al.
Publicado: (2019)

RNU6-1 in circulating exosomes differentiates GBM from non-neoplastic brain lesions and PCNSL but not from brain metastases
por: Puigdelloses, Montserrat, et al.
Publicado: (2020)

Correction: Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01
por: Vera, Beatriz, et al.
Publicado: (2016)

Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01
por: Vera, Beatriz, et al.
Publicado: (2016)

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report
por: Tejada, Sonia, et al.
Publicado: (2018)

The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models
por: Garcia-Moure, Marc, et al.
Publicado: (2019)

EPCT-04. RESULTS OF A PHASE 1 STUDY OF THE ONCOLYTIC ADENOVIRUS DNX-2401 WITH RADIOTHERAPY FOR NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
por: Garcia-Moure, Marc, et al.
Publicado: (2021)

Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells
por: Acanda de la Rocha, Arlet M., et al.
Publicado: (2016)

Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma
por: Zalacain, Marta, et al.
Publicado: (2020)

Oncolytic adenoviruses as a therapeutic approach for osteosarcoma: A new hope
por: Garcia-Moure, Marc, et al.
Publicado: (2016)

miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs
por: de la Rocha, Arlet María Acanda, et al.
Publicado: (2020)

Erratum: miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs
por: de la Rocha, Arlet María Acanda, et al.
Publicado: (2021)

Factors associated with a higher rate of distant failure after primary treatment for glioblastoma
por: Tejada, Sonia, et al.
Publicado: (2013)

Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma
por: Xipell, Enric, et al.
Publicado: (2016)

Erratum to: Factors associated with a higher rate of distant failure after primary treatment for glioblastoma
por: Tejada, Sonia, et al.
Publicado: (2013)

Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory
por: Martinez-Velez, Naiara, et al.
Publicado: (2022)

THER-02. EVALUATION OF THE ONCOLYTIC VIRUS DELTA24-RGD AS AN ANTI-TUMOR AGENT IN PRECLINICAL MODELS OF LOCALIZED AND DISSEMINATED AT/RT
por: Garcia-Moure, Marc, et al.
Publicado: (2020)

Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors
por: Xu, Cheng, et al.
Publicado: (2017)

DIPG-74. RE-IRRADIATION OF DIPG: DATA FROM THE INTERNATIONAL DIPG REGISTRY
por: Lafay-Cousin, Lucie, et al.
Publicado: (2020)

DIPG-50. A NOVEL ORTHOTOPIC PATIENT-DERIVED XENOGRAFT MODEL OF RADIATION-INDUCED GLIOMA
por: Whitehouse, Jacqueline, et al.
Publicado: (2020)

IMMU-01. THE ONCOLYTIC VIRUS DELTA-24-RGD IN COMBINATION WITH AN AGONISTIC CD40 MAB INDUCES A DURABLE AND SYNERGISTIC ANTI-TUMOR IMMUNE EFFECT IN DIPG PRECLINICAL MODELS
por: Labiano, Sara, et al.
Publicado: (2021)

DIPG-46. NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW
por: Lazow, Margot A, et al.
Publicado: (2020)

DIPG-48. DIPG THROUGH THE LOOKING GLASS
por: Senga, Sasi S
Publicado: (2023)

Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation
por: Lesueur, Paul, et al.
Publicado: (2018)

DIPG-16. Evaluation of myeloid component of DIPG microenvironment
por: Mishra, Deepak, et al.
Publicado: (2022)

DIPG-03. Therapeutic targeting of purine biosynthesis in DIPG
por: Mersich, Ian, et al.
Publicado: (2022)

Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors
por: Varela-Guruceaga, Maider, et al.
Publicado: (2018)

CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models
por: Puigdelloses, Montserrat, et al.
Publicado: (2021)

Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells
por: Saurty-Seerunghen, Mirca S., et al.
Publicado: (2019)

IMMU-08. MICROENVIRONMENT MODULATION BY TIM-3 BLOCKADE IMPROVES THE OUTCOME OF PRECLINICAL DIPG MODELS
por: Ausejo-Mauleon, Iker, et al.
Publicado: (2021)

THER-01. AWAKING THE IMMUNE SYSTEM WITH AN IMMUNO-ONCOLYTIC VIRUS AS A THERAPEUTIC STRATEGY FOR DIPGs
por: Laspidea, Virginia, et al.
Publicado: (2020)

DIPG-20. DETERMINATION AND MANAGEMENT OF HYDROCEPHALUS IN PATIENTS WITH DIPG, AN INSTITUTIONAL EXPERIENCE
por: Fonseca, Adriana, et al.
Publicado: (2020)

DIPG-70. DISORDERED DNA METHYLATION IN DIPG UNDERLIES PHENOTYPIC PLASTICITY
por: Koldobskiy, Michael, et al.
Publicado: (2020)

DIPG-59. UPREGULATION OF PRENATAL PONTINE ID1 SIGNALING IN DIPG
por: Harris, Micah K, et al.
Publicado: (2020)

DIPG-57. TRANSCRIPTOMIC AND PROTEOMIC ANALYSES OF DIPG RESPONSE TO ONC201
por: Sridharan, Sreepradha, et al.
Publicado: (2020)

DIPG-12. TARGETING EPIGENETIC MODIFIERS TO INDUCE IMMUNE SIGNALING IN DIPG
por: Tetens, Ashley, et al.
Publicado: (2020)

DIPG-52. Activators of the integrated stress response synergize to kill DIPG
por: Novak, Orlandi, et al.
Publicado: (2022)

THER-09. ONCOLYTIC ADENOVIRUS, DNX-2401, FOR NAIVE DIFFUSE INTRINSIC PONTINE GLIOMAS: A PHASE I CLINICAL TRIAL
por: Iñigo-Marco, Ignacio, et al.
Publicado: (2020)

SURG-05. MRI-GUIDED FOCUSED ULTRASOUND BLOOD-BRAIN BARRIER DISRUPTION INCREASES DRUG DELIVERY AND EFFICACY IN AN ORTHOTOPIC DIPG MODEL
por: Martinez, Payton, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sq5c82r1gf038b7p87divbuanb