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Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain

Diet-induced obesity (DIO) resulting from consumption of a high fat diet (HFD) attenuates normal neuronal responses to leptin and may contribute to the metabolic defense of an acquired higher body weight in humans; the molecular bases for the persistence of this defense are unknown. We measured the...

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Detalles Bibliográficos
Autores principales: Morabito, Michael V., Ravussin, Yann, Mueller, Bridget R., Skowronski, Alicja A., Watanabe, Kazuhisa, Foo, Kylie S., Lee, Samuel X., Lehmann, Anders, Hjorth, Stephan, Zeltser, Lori M., LeDuc, Charles A., Leibel, Rudolph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249166/
https://www.ncbi.nlm.nih.gov/pubmed/28107353
http://dx.doi.org/10.1371/journal.pone.0168226