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Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain
Diet-induced obesity (DIO) resulting from consumption of a high fat diet (HFD) attenuates normal neuronal responses to leptin and may contribute to the metabolic defense of an acquired higher body weight in humans; the molecular bases for the persistence of this defense are unknown. We measured the...
Autores principales: | Morabito, Michael V., Ravussin, Yann, Mueller, Bridget R., Skowronski, Alicja A., Watanabe, Kazuhisa, Foo, Kylie S., Lee, Samuel X., Lehmann, Anders, Hjorth, Stephan, Zeltser, Lori M., LeDuc, Charles A., Leibel, Rudolph L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249166/ https://www.ncbi.nlm.nih.gov/pubmed/28107353 http://dx.doi.org/10.1371/journal.pone.0168226 |
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