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Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation

The GTPase-accelerating protein, regulator of G-protein signalling 2 (RGS2) reduces signalling from G-protein-coupled receptors (GPCRs) that signal via Gαq. In humans, RGS2 expression is up-regulated by inhaled corticosteroids (ICSs) and long-acting β(2)-adrenoceptor agonists (LABAs) such that syner...

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Detalles Bibliográficos
Autores principales:	George, Tresa, Bell, Matthew, Chakraborty, Mainak, Siderovski, David P., Giembycz, Mark A., Newton, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249169/ https://www.ncbi.nlm.nih.gov/pubmed/28107494 http://dx.doi.org/10.1371/journal.pone.0170269

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