Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015

The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction-positive specimens (331 were previously reported and 149 were newly reported) collected from pediatric patients in Beijing, China, between 2003 and 2015 were analyzed. Genotype M4-5-7-2/P1 were the most prevalent ac...

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Autores principales: Sun, Hongmei, Xue, Guanhua, Yan, Chao, Li, Shaoli, Zhao, Hanqing, Feng, Yanling, Wang, Liqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249184/
https://www.ncbi.nlm.nih.gov/pubmed/28107399
http://dx.doi.org/10.1371/journal.pone.0170253
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author Sun, Hongmei
Xue, Guanhua
Yan, Chao
Li, Shaoli
Zhao, Hanqing
Feng, Yanling
Wang, Liqiong
author_facet Sun, Hongmei
Xue, Guanhua
Yan, Chao
Li, Shaoli
Zhao, Hanqing
Feng, Yanling
Wang, Liqiong
author_sort Sun, Hongmei
collection PubMed
description The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction-positive specimens (331 were previously reported and 149 were newly reported) collected from pediatric patients in Beijing, China, between 2003 and 2015 were analyzed. Genotype M4-5-7-2/P1 were the most prevalent across the 13-year study period, although the isolation and mutation rates for this genotype varied between the periods 2003–2007, 2008–2013, and 2014–2015. In addition, there was a close association between the M4-5-7-2 genotype and macrolide resistance.
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spelling pubmed-52491842017-02-06 Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015 Sun, Hongmei Xue, Guanhua Yan, Chao Li, Shaoli Zhao, Hanqing Feng, Yanling Wang, Liqiong PLoS One Research Article The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction-positive specimens (331 were previously reported and 149 were newly reported) collected from pediatric patients in Beijing, China, between 2003 and 2015 were analyzed. Genotype M4-5-7-2/P1 were the most prevalent across the 13-year study period, although the isolation and mutation rates for this genotype varied between the periods 2003–2007, 2008–2013, and 2014–2015. In addition, there was a close association between the M4-5-7-2 genotype and macrolide resistance. Public Library of Science 2017-01-20 /pmc/articles/PMC5249184/ /pubmed/28107399 http://dx.doi.org/10.1371/journal.pone.0170253 Text en © 2017 Sun et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sun, Hongmei
Xue, Guanhua
Yan, Chao
Li, Shaoli
Zhao, Hanqing
Feng, Yanling
Wang, Liqiong
Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title_full Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title_fullStr Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title_full_unstemmed Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title_short Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015
title_sort changes in molecular characteristics of mycoplasma pneumoniae in clinical specimens from children in beijing between 2003 and 2015
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249184/
https://www.ncbi.nlm.nih.gov/pubmed/28107399
http://dx.doi.org/10.1371/journal.pone.0170253
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