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Leptin influences estrogen metabolism and increases DNA adduct formation in breast cancer cells
OBJECTIVE: The elevated incidence of obesity has been paralleled with higher risks of breast cancer. High adiposity increases leptin secretion from adipose tissue, which in turn increases cancer cell proliferation. The interplay between leptin and estrogen is one of the mechanisms through which lept...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Editorial Committee of Cancer Biology & Medicine
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250609/ https://www.ncbi.nlm.nih.gov/pubmed/28154783 http://dx.doi.org/10.20892/j.issn.2095-3941.2016.0079 |