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Leptin influences estrogen metabolism and increases DNA adduct formation in breast cancer cells

OBJECTIVE: The elevated incidence of obesity has been paralleled with higher risks of breast cancer. High adiposity increases leptin secretion from adipose tissue, which in turn increases cancer cell proliferation. The interplay between leptin and estrogen is one of the mechanisms through which lept...

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Detalles Bibliográficos
Autores principales: Shouman, Samia, Wagih, Mohamed, Kamel, Marwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Editorial Committee of Cancer Biology & Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250609/
https://www.ncbi.nlm.nih.gov/pubmed/28154783
http://dx.doi.org/10.20892/j.issn.2095-3941.2016.0079