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Artefactual origin of biphasic cortical spike-LFP correlation

Electrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multip...

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Detalles Bibliográficos
Autor principal: Okun, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250656/
https://www.ncbi.nlm.nih.gov/pubmed/27629491
http://dx.doi.org/10.1007/s10827-016-0625-5
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author Okun, Michael
author_facet Okun, Michael
author_sort Okun, Michael
collection PubMed
description Electrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multiple studies, is likely an artefact introduced by high-pass filter of the neural data acquisition system when the actual stLFP has a single trough around the zero lag.
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spelling pubmed-52506562017-02-03 Artefactual origin of biphasic cortical spike-LFP correlation Okun, Michael J Comput Neurosci Article Electrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multiple studies, is likely an artefact introduced by high-pass filter of the neural data acquisition system when the actual stLFP has a single trough around the zero lag. Springer US 2016-09-14 2017 /pmc/articles/PMC5250656/ /pubmed/27629491 http://dx.doi.org/10.1007/s10827-016-0625-5 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Okun, Michael
Artefactual origin of biphasic cortical spike-LFP correlation
title Artefactual origin of biphasic cortical spike-LFP correlation
title_full Artefactual origin of biphasic cortical spike-LFP correlation
title_fullStr Artefactual origin of biphasic cortical spike-LFP correlation
title_full_unstemmed Artefactual origin of biphasic cortical spike-LFP correlation
title_short Artefactual origin of biphasic cortical spike-LFP correlation
title_sort artefactual origin of biphasic cortical spike-lfp correlation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250656/
https://www.ncbi.nlm.nih.gov/pubmed/27629491
http://dx.doi.org/10.1007/s10827-016-0625-5
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