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Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology

Inflammation is likely a key contributor to the pathogenesis of Parkinson’s disease (PD), a progressively debilitating neurodegenerative disease that is accompanied by a pathological accumulation of the α-synuclein protein in a staged manner through the brain. What leads to the accumulation of α-syn...

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Detalles Bibliográficos
Autores principales: Dzamko, Nicolas, Gysbers, Amanda, Perera, Gayathri, Bahar, Anita, Shankar, Amrita, Gao, Jianqun, Fu, YuHong, Halliday, Glenda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250664/
https://www.ncbi.nlm.nih.gov/pubmed/27888296
http://dx.doi.org/10.1007/s00401-016-1648-8