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Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology
Inflammation is likely a key contributor to the pathogenesis of Parkinson’s disease (PD), a progressively debilitating neurodegenerative disease that is accompanied by a pathological accumulation of the α-synuclein protein in a staged manner through the brain. What leads to the accumulation of α-syn...
Autores principales: | Dzamko, Nicolas, Gysbers, Amanda, Perera, Gayathri, Bahar, Anita, Shankar, Amrita, Gao, Jianqun, Fu, YuHong, Halliday, Glenda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250664/ https://www.ncbi.nlm.nih.gov/pubmed/27888296 http://dx.doi.org/10.1007/s00401-016-1648-8 |
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