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Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report

Spleen is an unusual location for hydatid cyst. Here we report a case of primary splenic hydatid cyst in a 41-yr-old Iranian woman from Yasuj, southwest of Iran. The patient had been admitted to Shahid Beheshti Hospital because of abdominal pain. Abdominal sonography revealed a hypoechoic lesion of...

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Autores principales: SARKARI, Bahador, FATEMIE SFEDAN, Asieh, MOSHFE, Abdolali, ABDOLAHI KHABISI, Samaneh, SAVARDASHTAKI, Amir, HOSSEINI, Farshad, SHAHBAZI, Ardavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251189/
https://www.ncbi.nlm.nih.gov/pubmed/28127372
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author SARKARI, Bahador
FATEMIE SFEDAN, Asieh
MOSHFE, Abdolali
ABDOLAHI KHABISI, Samaneh
SAVARDASHTAKI, Amir
HOSSEINI, Farshad
SHAHBAZI, Ardavan
author_facet SARKARI, Bahador
FATEMIE SFEDAN, Asieh
MOSHFE, Abdolali
ABDOLAHI KHABISI, Samaneh
SAVARDASHTAKI, Amir
HOSSEINI, Farshad
SHAHBAZI, Ardavan
author_sort SARKARI, Bahador
collection PubMed
description Spleen is an unusual location for hydatid cyst. Here we report a case of primary splenic hydatid cyst in a 41-yr-old Iranian woman from Yasuj, southwest of Iran. The patient had been admitted to Shahid Beheshti Hospital because of abdominal pain. Abdominal sonography revealed a hypoechoic lesion of 150 X 130 mm in the spleen, suggestive of hydatid cyst. Splenectomy was performed for the patient and surgical interventions revealed a hydatid cyst occupying most of splenic parenchyma. She was discharged on the 5 day of her operation. Postoperative diagnosis and confirmation of hydatid cyst was done by histopathological, molecular and serological approaches. Histopathological evaluation revealed the classical laminated layer of hydatid cyst. DNA was extracted from a part of cyst and PCR amplified. Sequencing and analysis of PCR product revealed that the isolate has the most similarity with G1 strain of Echinococcus granulosus. Patient’s serum was positive for IgG anti-hydatid cyst antibodies, using antigen-B ELISA.
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spelling pubmed-52511892017-01-26 Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report SARKARI, Bahador FATEMIE SFEDAN, Asieh MOSHFE, Abdolali ABDOLAHI KHABISI, Samaneh SAVARDASHTAKI, Amir HOSSEINI, Farshad SHAHBAZI, Ardavan Iran J Parasitol Case Report Spleen is an unusual location for hydatid cyst. Here we report a case of primary splenic hydatid cyst in a 41-yr-old Iranian woman from Yasuj, southwest of Iran. The patient had been admitted to Shahid Beheshti Hospital because of abdominal pain. Abdominal sonography revealed a hypoechoic lesion of 150 X 130 mm in the spleen, suggestive of hydatid cyst. Splenectomy was performed for the patient and surgical interventions revealed a hydatid cyst occupying most of splenic parenchyma. She was discharged on the 5 day of her operation. Postoperative diagnosis and confirmation of hydatid cyst was done by histopathological, molecular and serological approaches. Histopathological evaluation revealed the classical laminated layer of hydatid cyst. DNA was extracted from a part of cyst and PCR amplified. Sequencing and analysis of PCR product revealed that the isolate has the most similarity with G1 strain of Echinococcus granulosus. Patient’s serum was positive for IgG anti-hydatid cyst antibodies, using antigen-B ELISA. Tehran University of Medical Sciences 2016 /pmc/articles/PMC5251189/ /pubmed/28127372 Text en Copyright© Iranian Society of Parasitology & Tehran University of Medical Sciences This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
SARKARI, Bahador
FATEMIE SFEDAN, Asieh
MOSHFE, Abdolali
ABDOLAHI KHABISI, Samaneh
SAVARDASHTAKI, Amir
HOSSEINI, Farshad
SHAHBAZI, Ardavan
Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title_full Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title_fullStr Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title_full_unstemmed Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title_short Clinical and Molecular Evaluation of a Case of Giant Primary Splenic Hydatid Cyst: A Case Report
title_sort clinical and molecular evaluation of a case of giant primary splenic hydatid cyst: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251189/
https://www.ncbi.nlm.nih.gov/pubmed/28127372
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