Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease

A major feature of Alzheimer’s disease (AD) is the loss of noradrenergic locus coeruleus (LC) projection neurons that mediate attention, memory, and arousal. However, the extent to which the LC projection system degenerates during the initial stages of AD is still under investigation. To address thi...

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Detalles Bibliográficos
Autores principales: Kelly, Sarah C., He, Bin, Perez, Sylvia E., Ginsberg, Stephen D., Mufson, Elliott J., Counts, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251221/
https://www.ncbi.nlm.nih.gov/pubmed/28109312
http://dx.doi.org/10.1186/s40478-017-0411-2

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