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Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals
Background and purpose — The incidence of Perthes’ disease as reported in the literature varies widely between and within countries. The etiology of the disease is still unknown. Both environmental and genetic factors have been suggested to play a part in either causing the disease or increasing the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251271/ https://www.ncbi.nlm.nih.gov/pubmed/27587239 http://dx.doi.org/10.1080/17453674.2016.1227055 |
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author | Johansson, Torsten Lindblad, Maria Bladh, Marie Josefsson, Ann Sydsjö, Gunilla |
author_facet | Johansson, Torsten Lindblad, Maria Bladh, Marie Josefsson, Ann Sydsjö, Gunilla |
author_sort | Johansson, Torsten |
collection | PubMed |
description | Background and purpose — The incidence of Perthes’ disease as reported in the literature varies widely between and within countries. The etiology of the disease is still unknown. Both environmental and genetic factors have been suggested to play a part in either causing the disease or increasing the susceptibility of an individual. We determined the incidence of Perthes’ disease in Sweden and investigated possible relationships to parental socioeconomic status, ethnicity, marital status, mothers’ age when giving birth, parity, number of siblings, and smoking habits. Patients and methods — Six Swedish population-based registers were used, together covering all children born in Sweden from 1973 through 1993. Results — The incidence of Perthes’ disease in Sweden was 9.3 per 100,000 subjects. The ratio between boys and girls was 3.1:1. The educational level of the father and the mother of a child with Perthes’ disease was lower than in the controls. The incidence was lower when the fathers were in the highest income bracket (above the 90(th) percentile). A higher proportion of parents of Nordic lineage had children with Perthes’ disease than parental pairs with one or both who were not of such lineage. Interpretation — This study confirms that there is an association between the incidence of Perthes’ disease and the socioeconomic status of the parents. |
format | Online Article Text |
id | pubmed-5251271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-52512712017-02-04 Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals Johansson, Torsten Lindblad, Maria Bladh, Marie Josefsson, Ann Sydsjö, Gunilla Acta Orthop Children Background and purpose — The incidence of Perthes’ disease as reported in the literature varies widely between and within countries. The etiology of the disease is still unknown. Both environmental and genetic factors have been suggested to play a part in either causing the disease or increasing the susceptibility of an individual. We determined the incidence of Perthes’ disease in Sweden and investigated possible relationships to parental socioeconomic status, ethnicity, marital status, mothers’ age when giving birth, parity, number of siblings, and smoking habits. Patients and methods — Six Swedish population-based registers were used, together covering all children born in Sweden from 1973 through 1993. Results — The incidence of Perthes’ disease in Sweden was 9.3 per 100,000 subjects. The ratio between boys and girls was 3.1:1. The educational level of the father and the mother of a child with Perthes’ disease was lower than in the controls. The incidence was lower when the fathers were in the highest income bracket (above the 90(th) percentile). A higher proportion of parents of Nordic lineage had children with Perthes’ disease than parental pairs with one or both who were not of such lineage. Interpretation — This study confirms that there is an association between the incidence of Perthes’ disease and the socioeconomic status of the parents. Taylor & Francis 2017-02 2016-08-30 /pmc/articles/PMC5251271/ /pubmed/27587239 http://dx.doi.org/10.1080/17453674.2016.1227055 Text en © 2016 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation. https://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (https://creativecommons.org/licenses/by-nc/3.0) |
spellingShingle | Children Johansson, Torsten Lindblad, Maria Bladh, Marie Josefsson, Ann Sydsjö, Gunilla Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title | Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title_full | Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title_fullStr | Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title_full_unstemmed | Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title_short | Incidence of Perthes’ disease in children born between 1973 and 1993: A Swedish nationwide cohort study of 2.1 million individuals |
title_sort | incidence of perthes’ disease in children born between 1973 and 1993: a swedish nationwide cohort study of 2.1 million individuals |
topic | Children |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251271/ https://www.ncbi.nlm.nih.gov/pubmed/27587239 http://dx.doi.org/10.1080/17453674.2016.1227055 |
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