Adjusting Overall Survival Estimates after Treatment Switching: a Case Study in Metastatic Castration-Resistant Prostate Cancer

BACKGROUND: If patients in oncology trials receive subsequent therapy, standard intention-to-treat (ITT) analyses may inaccurately estimate the overall survival (OS) effect of the investigational product. In this context, a post-hoc analysis of the phase 3 PREVAIL study was performed with the aim to...

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Detalles Bibliográficos
Autores principales: Skaltsa, Konstantina, Ivanescu, Cristina, Naidoo, Shevani, Phung, De, Holmstrom, Stefan, Latimer, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253154/
https://www.ncbi.nlm.nih.gov/pubmed/27981431
http://dx.doi.org/10.1007/s11523-016-0472-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253154/
https://www.ncbi.nlm.nih.gov/pubmed/27981431
http://dx.doi.org/10.1007/s11523-016-0472-3

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