Chronic Inactivation of the Orbitofrontal Cortex Increases Anxiety-Like Behavior and Impulsive Aggression, but Decreases Depression-Like Behavior in Rats

The orbitofrontal cortex (OFC) is involved in emotional processing, and orbitofrontal abnormalities have often been observed in various affective disorders. Thus, chronic dysfunction of the OFC may cause symptoms of affective disorders, such as anxiety, depression and impulsivity. Previous studies h...

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Detalles Bibliográficos
Autores principales: Kuniishi, Hiroshi, Ichisaka, Satoshi, Matsuda, Sae, Futora, Eri, Harada, Riho, Hata, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253363/
https://www.ncbi.nlm.nih.gov/pubmed/28167902
http://dx.doi.org/10.3389/fnbeh.2016.00250

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