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C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis

Gouty arthritis results from the generation of monosodium urate (MSU) crystals within joints. These MSU crystals elicit acute inflammation characterized by massive infiltration of neutrophils and monocytes that are mobilized by the pro-inflammatory cytokine IL-1β. MSU crystals also activate the comp...

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Detalles Bibliográficos
Autores principales:	Khameneh, Hanif J., Ho, Adrian W. S., Laudisi, Federica, Derks, Heidi, Kandasamy, Matheswaran, Sivasankar, Baalasubramanian, Teng, Gim Gee, Mortellaro, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253373/ https://www.ncbi.nlm.nih.gov/pubmed/28167912 http://dx.doi.org/10.3389/fphar.2017.00010

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