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Direct PIP(2) binding mediates stable oligomer formation of the serotonin transporter

The human serotonin transporter (hSERT) mediates uptake of serotonin from the synaptic cleft and thereby terminates serotonergic signalling. We have previously found by single-molecule microscopy that SERT forms stable higher-order oligomers of differing stoichiometry at the plasma membrane of livin...

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Detalles Bibliográficos
Autores principales:	Anderluh, Andreas, Hofmaier, Tina, Klotzsch, Enrico, Kudlacek, Oliver, Stockner, Thomas, Sitte, Harald H., Schütz, Gerhard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253637/ https://www.ncbi.nlm.nih.gov/pubmed/28102201 http://dx.doi.org/10.1038/ncomms14089

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