The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells

The mitotic checkpoint complex (MCC) is formed from two sub-complexes of CDC20-MAD2 and BUBR1-BUB3, and current models suggest that it is generated exclusively by the kinetochores after nuclear envelope breakdown (NEBD). However, neither sub-complex has been visualised in vivo, and when and where th...

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Detalles Bibliográficos
Autores principales: Li, Jianquan, Dang, Nanmao, Wood, Daniel James, Huang, Jun-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253641/
https://www.ncbi.nlm.nih.gov/pubmed/28112196
http://dx.doi.org/10.1038/srep41072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253641/
https://www.ncbi.nlm.nih.gov/pubmed/28112196
http://dx.doi.org/10.1038/srep41072

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