The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells

MicroRNAs act posttranscriptionally to suppress multiple target genes within a cell population. To what extent this multi-target suppression occurs in individual cells and how it impacts transcriptional heterogeneity and gene co-expression remains unknown. Here we used single-cell sequencing combine...

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Detalles Bibliográficos
Autores principales: Gambardella, Gennaro, Carissimo, Annamaria, Chen, Amy, Cutillo, Luisa, Nowakowski, Tomasz J., di Bernardo, Diego, Blelloch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253645/
https://www.ncbi.nlm.nih.gov/pubmed/28102192
http://dx.doi.org/10.1038/ncomms14126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253645/
https://www.ncbi.nlm.nih.gov/pubmed/28102192
http://dx.doi.org/10.1038/ncomms14126

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