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Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses

The assembly of the first centrosome occurs upon fertilisation when male centrioles recruit pericentriolar material (PCM) from the egg cytoplasm. The mechanisms underlying the proper assembly of centrosomes during early embryogenesis remain obscure. We identify Wdr8 as a novel maternally essential p...

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Detalles Bibliográficos
Autores principales:	Inoue, Daigo, Stemmer, Manuel, Thumberger, Thomas, Ruppert, Thomas, Bärenz, Felix, Wittbrodt, Joachim, Gruss, Oliver J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253655/ https://www.ncbi.nlm.nih.gov/pubmed/28098238 http://dx.doi.org/10.1038/ncomms14090

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