Thermal activation of ‘allosteric-like’ large-scale motions in a eukaryotic Lactate Dehydrogenase

Conformational changes occurring during the enzymatic turnover are essential for the regulation of protein functionality. Individuating the protein regions involved in these changes and the associated mechanical modes is still a challenge at both experimental and theoretical levels. We present here...

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Detalles Bibliográficos
Autores principales: Katava, Marina, Maccarini, Marco, Villain, Guillaume, Paciaroni, Alessandro, Sztucki, Michael, Ivanova, Oxana, Madern, Dominique, Sterpone, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253740/
https://www.ncbi.nlm.nih.gov/pubmed/28112231
http://dx.doi.org/10.1038/srep41092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253740/
https://www.ncbi.nlm.nih.gov/pubmed/28112231
http://dx.doi.org/10.1038/srep41092

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