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Thermal activation of ‘allosteric-like’ large-scale motions in a eukaryotic Lactate Dehydrogenase
Conformational changes occurring during the enzymatic turnover are essential for the regulation of protein functionality. Individuating the protein regions involved in these changes and the associated mechanical modes is still a challenge at both experimental and theoretical levels. We present here...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253740/ https://www.ncbi.nlm.nih.gov/pubmed/28112231 http://dx.doi.org/10.1038/srep41092 |