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Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance

Despite good treatment results in localized prostate tumors, advanced disease stages usually have a pronounced resistance to chemotherapy and radiotherapy. The membrane protein caveolin-1 (Cav1) functions here as an important oncogene. Therefore we examined the impact of stromal Cav1 expression for...

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Detalles Bibliográficos
Autores principales: Panic, Andrej, Ketteler, Julia, Reis, Henning, Sak, Ali, Herskind, Carsten, Maier, Patrick, Rübben, Herbert, Jendrossek, Verena, Klein, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255553/
https://www.ncbi.nlm.nih.gov/pubmed/28112237
http://dx.doi.org/10.1038/srep41138

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