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The expression of SIRT1 regulates the metastaticplasticity of chondrosarcoma cells by inducing epithelial-mesenchymal transition

SIRT1 belongs to the mammalian sirtuin family and plays an important role in deacetylating histone and nonhistone proteins. It is reported that SIRT1 is associated with tumor metastasis in several kinds of tumors. However, the effect of SIRT1 on the metastasis of chondrosarcoma cells is still unknow...

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Detalles Bibliográficos
Autores principales: Feng, Helin, Wang, Jin, Xu, Jianfa, Xie, Congcong, Gao, Fulu, Li, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255567/
https://www.ncbi.nlm.nih.gov/pubmed/28112277
http://dx.doi.org/10.1038/srep41203

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