Cargando…
Warfarin related acute kidney injury: A case report
Warfarin is an oral anticoagulant used extensively in clinical practice; However, its side-effect of causing renal damage has been recently detected. The mechanism leading to renal damage is glomerular hemorrhage and red blood cell tubular casts prothrombin time. Recently, it was found that warfarin...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255998/ https://www.ncbi.nlm.nih.gov/pubmed/28182051 http://dx.doi.org/10.4103/0971-4065.177142 |
_version_ | 1782498627928719360 |
---|---|
author | Mendonca, S. Gupta, D. Valsan, A. Tewari, R. |
author_facet | Mendonca, S. Gupta, D. Valsan, A. Tewari, R. |
author_sort | Mendonca, S. |
collection | PubMed |
description | Warfarin is an oral anticoagulant used extensively in clinical practice; However, its side-effect of causing renal damage has been recently detected. The mechanism leading to renal damage is glomerular hemorrhage and red blood cell tubular casts prothrombin time. Recently, it was found that warfarin causes renal damage in patients with chronic kidney disease and is also associated with progression of renal disease. Warfarin causing acute kidney injury in patients with normal renal function is a rare manifestation. It is important to be aware of this condition as its innocuous presence can lead to chronic kidney disease if not corrected in time. Further studies have also found that novel oral anticoagulants such as dabigatran also cause a similar syndrome and hence a new term called anticoagulant-related nephropathy is now in vogue. |
format | Online Article Text |
id | pubmed-5255998 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-52559982017-02-08 Warfarin related acute kidney injury: A case report Mendonca, S. Gupta, D. Valsan, A. Tewari, R. Indian J Nephrol Case Report Warfarin is an oral anticoagulant used extensively in clinical practice; However, its side-effect of causing renal damage has been recently detected. The mechanism leading to renal damage is glomerular hemorrhage and red blood cell tubular casts prothrombin time. Recently, it was found that warfarin causes renal damage in patients with chronic kidney disease and is also associated with progression of renal disease. Warfarin causing acute kidney injury in patients with normal renal function is a rare manifestation. It is important to be aware of this condition as its innocuous presence can lead to chronic kidney disease if not corrected in time. Further studies have also found that novel oral anticoagulants such as dabigatran also cause a similar syndrome and hence a new term called anticoagulant-related nephropathy is now in vogue. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5255998/ /pubmed/28182051 http://dx.doi.org/10.4103/0971-4065.177142 Text en Copyright: © 2017 Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Mendonca, S. Gupta, D. Valsan, A. Tewari, R. Warfarin related acute kidney injury: A case report |
title | Warfarin related acute kidney injury: A case report |
title_full | Warfarin related acute kidney injury: A case report |
title_fullStr | Warfarin related acute kidney injury: A case report |
title_full_unstemmed | Warfarin related acute kidney injury: A case report |
title_short | Warfarin related acute kidney injury: A case report |
title_sort | warfarin related acute kidney injury: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255998/ https://www.ncbi.nlm.nih.gov/pubmed/28182051 http://dx.doi.org/10.4103/0971-4065.177142 |
work_keys_str_mv | AT mendoncas warfarinrelatedacutekidneyinjuryacasereport AT guptad warfarinrelatedacutekidneyinjuryacasereport AT valsana warfarinrelatedacutekidneyinjuryacasereport AT tewarir warfarinrelatedacutekidneyinjuryacasereport |