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Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol
Toll-like receptors (TLRs) are major players of the innate immune system. Once activated, they trigger a signalling cascade that leads to NF-κB translocation from the cytoplasm to the nucleus. Single cell analysis shows that NF-κB signalling dynamics are a critical determinant of transcriptional reg...
Autores principales: | Caballero, Ignacio, Boyd, James, Almiñana, Carmen, Sánchez-López, Javier A., Basatvat, Shaghayegh, Montazeri, Mehrnaz, Maslehat Lay, Nasim, Elliott, Sarah, Spiller, David G., White, Michael R. H., Fazeli, Alireza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256028/ https://www.ncbi.nlm.nih.gov/pubmed/28112187 http://dx.doi.org/10.1038/srep40981 |
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