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In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent

BACKGROUND: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However,...

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Autores principales: METİN, Bayram, YILMAZ, Neziha, BEYHAN, Yunus Emre, BABÜR, Cahit, SİPAHİ, Mesut, EDE, Hüseyin, İNTEPE, Yavuz Selim, ARSLAN, Ergin, ATALAY, Tugay, ÖZDAMAR, Mustafa Yaşar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256059/
https://www.ncbi.nlm.nih.gov/pubmed/28127348
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author METİN, Bayram
YILMAZ, Neziha
BEYHAN, Yunus Emre
BABÜR, Cahit
SİPAHİ, Mesut
EDE, Hüseyin
İNTEPE, Yavuz Selim
ARSLAN, Ergin
ATALAY, Tugay
ÖZDAMAR, Mustafa Yaşar
author_facet METİN, Bayram
YILMAZ, Neziha
BEYHAN, Yunus Emre
BABÜR, Cahit
SİPAHİ, Mesut
EDE, Hüseyin
İNTEPE, Yavuz Selim
ARSLAN, Ergin
ATALAY, Tugay
ÖZDAMAR, Mustafa Yaşar
author_sort METİN, Bayram
collection PubMed
description BACKGROUND: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However, the germicidal efficacy of the Ankaferd Blood Stopper® (ABS) has not been investigated. Thus, we compared the efficacy of ABS for hydatid cysts with that of other germicidal agents. METHODS: Lung and liver tissues containing hydatid cyst liquid were collected from slaughterhouses. Six samples of each cyst were randomly allocated into different groups as follows: 20% hypertonic NaCl, betadine solution, ABS, 20% liquefied Andazole solution, 0.1% eosin, and distilled water. All groups were examined microscopically at 5, 10, and 15 min after treatment began to determine protoscolece viability rates. RESULTS: The most efficacious germicidal agent at 5 min was ABS, and betadine and hypertonic NaCl had similar efficacies. Betadine, ABS, and hypertonic NaCl showed similar efficacies at 15 min. CONCLUSION: ABS was an effective germicidal agent to treat hydatid cysts.
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spelling pubmed-52560592017-01-26 In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent METİN, Bayram YILMAZ, Neziha BEYHAN, Yunus Emre BABÜR, Cahit SİPAHİ, Mesut EDE, Hüseyin İNTEPE, Yavuz Selim ARSLAN, Ergin ATALAY, Tugay ÖZDAMAR, Mustafa Yaşar Iran J Parasitol Short Communication BACKGROUND: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However, the germicidal efficacy of the Ankaferd Blood Stopper® (ABS) has not been investigated. Thus, we compared the efficacy of ABS for hydatid cysts with that of other germicidal agents. METHODS: Lung and liver tissues containing hydatid cyst liquid were collected from slaughterhouses. Six samples of each cyst were randomly allocated into different groups as follows: 20% hypertonic NaCl, betadine solution, ABS, 20% liquefied Andazole solution, 0.1% eosin, and distilled water. All groups were examined microscopically at 5, 10, and 15 min after treatment began to determine protoscolece viability rates. RESULTS: The most efficacious germicidal agent at 5 min was ABS, and betadine and hypertonic NaCl had similar efficacies. Betadine, ABS, and hypertonic NaCl showed similar efficacies at 15 min. CONCLUSION: ABS was an effective germicidal agent to treat hydatid cysts. Tehran University of Medical Sciences 2016 /pmc/articles/PMC5256059/ /pubmed/28127348 Text en Copyright© Iranian Society of Parasitology & Tehran University of Medical Sciences This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Short Communication
METİN, Bayram
YILMAZ, Neziha
BEYHAN, Yunus Emre
BABÜR, Cahit
SİPAHİ, Mesut
EDE, Hüseyin
İNTEPE, Yavuz Selim
ARSLAN, Ergin
ATALAY, Tugay
ÖZDAMAR, Mustafa Yaşar
In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_full In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_fullStr In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_full_unstemmed In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_short In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_sort in vitro efficacy of the ankaferd galenic hemostatic extract as a germicidal agent
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256059/
https://www.ncbi.nlm.nih.gov/pubmed/28127348
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