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Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction
Previously, we found that brain‐derived neurotrophic factor (BDNF) signaling through the high‐affinity tropomyosin‐related kinase receptor subtype B (TrkB) enhances neuromuscular transmission in the diaphragm muscle. However, there is an age‐related loss of this effect of BDNF/TrkB signaling that ma...
Autores principales: | Greising, Sarah M., Vasdev, Amrit K., Zhan, Wen‐Zhi, Sieck, Gary C., Mantilla, Carlos B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256161/ https://www.ncbi.nlm.nih.gov/pubmed/28082429 http://dx.doi.org/10.14814/phy2.13103 |
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