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Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages

BACKGROUND: Delayed hypersensitivity plays a large role in the pathogenesis of tuberculous pleural effusion (TPE). Macrophages infected with live Mycobacterium tuberculosis (MTB) increase the levels of adenosine deaminase2 (ADA2) in the pleural fluid of TPE patients. However, it is as yet unclear wh...

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Detalles Bibliográficos
Autores principales: Bae, Mi Jung, Ryu, Suyeon, Kim, Ha-Jeong, Cha, Seung Ick, Kim, Chang Ho, Lee, Jaehee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256347/
https://www.ncbi.nlm.nih.gov/pubmed/28119750
http://dx.doi.org/10.4046/trd.2017.80.1.77