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How close are we to standardised extended RAS gene mutation testing? The UK NEQAS evaluation

AIMS: Since 2008, KRAS mutation status in exon 2 has been used to predict response to anti-EGFR therapies. Recent evidence has demonstrated that NRAS status is also predictive of response. Several retrospective ‘extended RAS’ analyses have been performed on clinical trial material. Despite this, are...

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Detalles Bibliográficos
Autores principales: Richman, Susan D, Fairley, Jennifer, Butler, Rachel, Deans, Zandra C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256378/
https://www.ncbi.nlm.nih.gov/pubmed/27681846
http://dx.doi.org/10.1136/jclinpath-2016-203822

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