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Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks

Mechanistic mathematical modeling of biochemical reaction networks using ordinary differential equation (ODE) models has improved our understanding of small- and medium-scale biological processes. While the same should in principle hold for large- and genome-scale processes, the computational method...

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Detalles Bibliográficos
Autores principales: Fröhlich, Fabian, Kaltenbacher, Barbara, Theis, Fabian J., Hasenauer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256869/
https://www.ncbi.nlm.nih.gov/pubmed/28114351
http://dx.doi.org/10.1371/journal.pcbi.1005331