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Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks
Mechanistic mathematical modeling of biochemical reaction networks using ordinary differential equation (ODE) models has improved our understanding of small- and medium-scale biological processes. While the same should in principle hold for large- and genome-scale processes, the computational method...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256869/ https://www.ncbi.nlm.nih.gov/pubmed/28114351 http://dx.doi.org/10.1371/journal.pcbi.1005331 |