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NOD1(CARD) Might Be Using Multiple Interfaces for RIP2-Mediated CARD-CARD Interaction: Insights from Molecular Dynamics Simulation

The nucleotide-binding and oligomerization domain (NOD)-containing protein 1 (NOD1) plays the pivotal role in host-pathogen interface of innate immunity and triggers immune signalling pathways for the maturation and release of pro-inflammatory cytokines. Upon the recognition of iE-DAP, NOD1 self-oli...

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Detalles Bibliográficos
Autores principales: Maharana, Jitendra, Pradhan, Sukanta Kumar, De, Sachinandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256935/
https://www.ncbi.nlm.nih.gov/pubmed/28114344
http://dx.doi.org/10.1371/journal.pone.0170232