The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven transmembrane G protein-coupled receptor is known t...

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Detalles Bibliográficos
Autores principales: Jahny, Elisabeth, Yang, Hai, Liu, Bin, Jahnke, Beatrix, Lademann, Franziska, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Aust, Daniela E., Pilarsky, Christian, Denz, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256936/
https://www.ncbi.nlm.nih.gov/pubmed/28114355
http://dx.doi.org/10.1371/journal.pone.0170390

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