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Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis

Hydrocephalus is an uncommon presentation of neurosarcoidosis. We discuss the case of a 67‐year‐old woman with a prior diagnosis of hypothyroidism, systemic hypertension, and lung sarcoidosis who presented with a 1‐month history of progressive impairment of consciousness leading to prostration and l...

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Autores principales: Labarca, Gonzalo, Ramirez, Romina, Monsalve, Ximena, Mira‐Avendano, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256957/
https://www.ncbi.nlm.nih.gov/pubmed/28127435
http://dx.doi.org/10.1002/rcr2.182
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author Labarca, Gonzalo
Ramirez, Romina
Monsalve, Ximena
Mira‐Avendano, Isabel
author_facet Labarca, Gonzalo
Ramirez, Romina
Monsalve, Ximena
Mira‐Avendano, Isabel
author_sort Labarca, Gonzalo
collection PubMed
description Hydrocephalus is an uncommon presentation of neurosarcoidosis. We discuss the case of a 67‐year‐old woman with a prior diagnosis of hypothyroidism, systemic hypertension, and lung sarcoidosis who presented with a 1‐month history of progressive impairment of consciousness leading to prostration and loss of sphincter control. At admission, patient was febrile with altered speech and without focalization. Laboratory results showed leucocytosis and mild anaemia. Cerebrospinal fluid (CSF) analysis was characterized by mild elevated protein level, increased cell count, normal glucose and adenosine deaminase (ADA), negative cytology, and no bacterial isolations. Electroencephalogram showed toxic‐metabolic encephalopathy. Computed tomography (CT) of the brain revealed hydrocephalus without structural damage, and magnetic resonance imaging of the brain demonstrated non‐specific diffuse meningeal enhancement and periventricular changes supporting normal pressure hydrocephalus. Chest X‐ray showed mediastinal adenopathy and parenchymatous lesions, consistent with stage II lung sarcoidosis. A ventriculoperitoneal shunt was installed, and the patient experienced rapid improvement in her symptoms.
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spelling pubmed-52569572017-01-26 Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis Labarca, Gonzalo Ramirez, Romina Monsalve, Ximena Mira‐Avendano, Isabel Respirol Case Rep Case Reports Hydrocephalus is an uncommon presentation of neurosarcoidosis. We discuss the case of a 67‐year‐old woman with a prior diagnosis of hypothyroidism, systemic hypertension, and lung sarcoidosis who presented with a 1‐month history of progressive impairment of consciousness leading to prostration and loss of sphincter control. At admission, patient was febrile with altered speech and without focalization. Laboratory results showed leucocytosis and mild anaemia. Cerebrospinal fluid (CSF) analysis was characterized by mild elevated protein level, increased cell count, normal glucose and adenosine deaminase (ADA), negative cytology, and no bacterial isolations. Electroencephalogram showed toxic‐metabolic encephalopathy. Computed tomography (CT) of the brain revealed hydrocephalus without structural damage, and magnetic resonance imaging of the brain demonstrated non‐specific diffuse meningeal enhancement and periventricular changes supporting normal pressure hydrocephalus. Chest X‐ray showed mediastinal adenopathy and parenchymatous lesions, consistent with stage II lung sarcoidosis. A ventriculoperitoneal shunt was installed, and the patient experienced rapid improvement in her symptoms. John Wiley & Sons, Ltd 2016-08-26 /pmc/articles/PMC5256957/ /pubmed/28127435 http://dx.doi.org/10.1002/rcr2.182 Text en © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Labarca, Gonzalo
Ramirez, Romina
Monsalve, Ximena
Mira‐Avendano, Isabel
Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title_full Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title_fullStr Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title_full_unstemmed Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title_short Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
title_sort dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256957/
https://www.ncbi.nlm.nih.gov/pubmed/28127435
http://dx.doi.org/10.1002/rcr2.182
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