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Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis
BACKGROUND: Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a granuloma response at injection site by 4–6 weeks. Previous work indicates proteins as the possible trigger of this reaction. We aim...
Autores principales: | Eberhardt, Christian, Thillai, Muhunthan, Parker, Robert, Siddiqui, Nazneen, Potiphar, Lee, Goldin, Rob, Timms, John F., Wells, Athol U., Kon, Onn M., Wickremasinghe, Melissa, Mitchell, Donald, Weeks, Mark E., Lalvani, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256960/ https://www.ncbi.nlm.nih.gov/pubmed/28114394 http://dx.doi.org/10.1371/journal.pone.0170285 |
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