Cargando…
High Glucose-Mediated STAT3 Activation in Endometrial Cancer Is Inhibited by Metformin: Therapeutic Implications for Endometrial Cancer
OBJECTIVES: STAT3 is over-expressed in endometrial cancer, and diabetes is a risk factor for the development of type 1 endometrial cancer. We therefore investigated whether glucose concentrations influence STAT3 expression in type 1 endometrial cancer, and whether such STAT3 expression might be inhi...
Autores principales: | Wallbillich, John J., Josyula, Srirama, Saini, Uksha, Zingarelli, Roman A., Dorayappan, Kalpana Deepa Priya, Riley, Maria K., Wanner, Ross A., Cohn, David E., Selvendiran, Karuppaiyah |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256996/ https://www.ncbi.nlm.nih.gov/pubmed/28114390 http://dx.doi.org/10.1371/journal.pone.0170318 |
Ejemplares similares
-
Correction: Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus
por: Saini, Uksha, et al.
Publicado: (2023) -
Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus
por: Saini, Uksha, et al.
Publicado: (2022) -
Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor
por: McCann, Georgia A., et al.
Publicado: (2014) -
Metformin as a Therapeutic Target in Endometrial Cancers
por: Lee, Teresa Y., et al.
Publicado: (2018) -
Quality of life in endometrial cancer survivors by grade of disease
por: Banning, K., et al.
Publicado: (2023)