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Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

The comprehensive understanding of cellular signaling pathways remains a challenge due to multiple layers of regulation that may become evident only when the pathway is probed at different levels or critical nodes are eliminated. To discover regulatory mechanisms in canonical WNT signaling, we condu...

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Detalles Bibliográficos
Autores principales:	Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257257/ https://www.ncbi.nlm.nih.gov/pubmed/27996937 http://dx.doi.org/10.7554/eLife.21459

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