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Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away

The most significant outbreak of Legionella pneumophila, or Legionnaires’ Disease, ever registered in Portugal occurred in 2014, and was considered one of the largest in European history. This relatively rare infection has a dire prognosis if not timely identified and correctly treated, presenting w...

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Detalles Bibliográficos
Autores principales: Jacob, Miguel, Ramos, Helena C, Morgado, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258191/
https://www.ncbi.nlm.nih.gov/pubmed/28123918
http://dx.doi.org/10.7759/cureus.937
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author Jacob, Miguel
Ramos, Helena C
Morgado, Bruno
author_facet Jacob, Miguel
Ramos, Helena C
Morgado, Bruno
author_sort Jacob, Miguel
collection PubMed
description The most significant outbreak of Legionella pneumophila, or Legionnaires’ Disease, ever registered in Portugal occurred in 2014, and was considered one of the largest in European history. This relatively rare infection has a dire prognosis if not timely identified and correctly treated, presenting with a high lethality rate. We describe a case of infection by Legionella pneumophila in a previously healthy individual during an outbreak that originated 300 kilometers away from our hospital. The patient presented to the Emergency Department and after an initial assessment, was admitted to the Intensive Care Unit (ICU). He underwent supportive treatment with invasive mechanical ventilation and antibiotic therapy, having been discharged with functional improvement 21 days after admission. During follow-up, the patient presented well without residual clinical or radiological findings. Prompt management following established guidelines allowed for the appropriate treatment and a favorable prognosis. This case serves as a reminder that early management is important, healthy individuals without known risk factors may present with severe infection, and there is the possibility for individual cases of Legionellosis to present far from the outbreak source.
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spelling pubmed-52581912017-01-25 Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away Jacob, Miguel Ramos, Helena C Morgado, Bruno Cureus Pulmonology The most significant outbreak of Legionella pneumophila, or Legionnaires’ Disease, ever registered in Portugal occurred in 2014, and was considered one of the largest in European history. This relatively rare infection has a dire prognosis if not timely identified and correctly treated, presenting with a high lethality rate. We describe a case of infection by Legionella pneumophila in a previously healthy individual during an outbreak that originated 300 kilometers away from our hospital. The patient presented to the Emergency Department and after an initial assessment, was admitted to the Intensive Care Unit (ICU). He underwent supportive treatment with invasive mechanical ventilation and antibiotic therapy, having been discharged with functional improvement 21 days after admission. During follow-up, the patient presented well without residual clinical or radiological findings. Prompt management following established guidelines allowed for the appropriate treatment and a favorable prognosis. This case serves as a reminder that early management is important, healthy individuals without known risk factors may present with severe infection, and there is the possibility for individual cases of Legionellosis to present far from the outbreak source. Cureus 2016-12-21 /pmc/articles/PMC5258191/ /pubmed/28123918 http://dx.doi.org/10.7759/cureus.937 Text en Copyright © 2016, Jacob et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pulmonology
Jacob, Miguel
Ramos, Helena C
Morgado, Bruno
Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title_full Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title_fullStr Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title_full_unstemmed Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title_short Severe Legionella Pneumophila Infection in an Immunocompetent Patient: A Success Story 300 Kilometers Away
title_sort severe legionella pneumophila infection in an immunocompetent patient: a success story 300 kilometers away
topic Pulmonology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258191/
https://www.ncbi.nlm.nih.gov/pubmed/28123918
http://dx.doi.org/10.7759/cureus.937
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