Veliparib in combination with whole-brain radiation therapy for patients with brain metastases from non-small cell lung cancer: results of a randomized, global, placebo-controlled study

Veliparib is a potent, orally bioavailable, poly (adenosine diphosphate-ribose) polymerase (PARP) inhibitor that crosses the blood–brain barrier and has been shown to potentiate the effects of radiation in preclinical and early clinical studies. This phase 2, randomized, global study evaluated the e...

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Detalles Bibliográficos
Autores principales: Chabot, Pierre, Hsia, Te-Chun, Ryu, Jeong-Seon, Gorbunova, Vera, Belda-Iniesta, Cristobal, Ball, David, Kio, Ebenezer, Mehta, Minesh, Papp, Katherine, Qin, Qin, Qian, Jane, Holen, Kyle D., Giranda, Vince, Suh, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258788/
https://www.ncbi.nlm.nih.gov/pubmed/27655223
http://dx.doi.org/10.1007/s11060-016-2275-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258788/
https://www.ncbi.nlm.nih.gov/pubmed/27655223
http://dx.doi.org/10.1007/s11060-016-2275-x

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